Development and Challenges of Using Serratiopeptidase Enzymes as Anti-Inflammatory in the Present Era: Literature Review

Pengembangan dan Tantangan Penggunaan Enzim Serratiopeptidase Sebagai Antiinflamasi di Era Masa Kini: Literature Review

  • Faisal Akhmal Muslikh Mahasiswa Magister Ilmu Farmasi, Departemen Ilmu Kefarmasian, Fakultas Farmasi, Universitas Airlangga, Surabaya
  • Sukardiman Departemen Ilmu Kefarmasian, Fakultas Farmasi, Universitas Airlangga, Surabaya
Keywords: serratiopeptidase enzyme, anti-inflammatory, development, challenge

Abstract

Enzymes are proteins that control and carry out metabolic activities in the body, either directly or indirectly. Enzymes have various advantages over traditional pharmaceuticals in terms of therapeutic efficacy and toxicity. They have great specificity and affinity for their target, minimizing toxicity. Use the terms "Serratiopeptidase enzyme" and "inflammation" to search publications in Google Scholar, Sciencedirect, SAGE journal, and Pubmed databases. According to ten articles, the serratiopeptidase enzyme has been shown to have an anti-inflammatory effect by reducing inflammatory cytokines and adhesion molecules, thereby regulating the movement of inflammatory cells to the site of inflammation, which in clinical trials can reduce swelling of edema and metabolism of scar tissue in the body.

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Published
2022-07-31
How to Cite
Muslikh, F. A., & Sukardiman. (2022). Development and Challenges of Using Serratiopeptidase Enzymes as Anti-Inflammatory in the Present Era: Literature Review: Pengembangan dan Tantangan Penggunaan Enzim Serratiopeptidase Sebagai Antiinflamasi di Era Masa Kini: Literature Review. Journal Pharmasci (Journal of Pharmacy and Science), 7(2), 71-75. https://doi.org/10.53342/pharmasci.v7i2.283