Prescribing Profile among Pregnancy in the Outpatient Pharmacy Installation of Bokor Hospital, Malang
Prescribing Profile of Pregnant Women at the Outpatient Pharmacy Installation of Bokor Hospital Malang Regency
AbstractDrug therapy in pregnant women is important because it can cross the placental blood barrier so that it has a negative effect on fetal development. This study aims to determine the profile of drug prescription in pregnant women including drug therapy class, drug name, drug category based on fetal safety. This study aims to determine the profile of drug prescribing in pregnant women including drug therapy class, type of drug and drug category based on safety for the fetus. The study used retrospective data in the form of 100 prescription sheets at the Outpatient Pharmacy Installation of Bokor Hospital, Malang Regency, the period July-September 2021. The results showed that there were 14 different classes of drug therapy prescribed to pregnant women. The number of vitamin and mineral prescription cases was 116 prescriptions (54%) with 100 prescriptions (46%) consisting of 13 drug therapy classes. Five percentages of prescriptions were vitamin-mineral 54%, analgesic 18.5%, tocolytic 5.1%. 4.6% and antiemetics 4.2%. Four types of drugs were prescribed from each therapeutic class, namely mefenamic acid (analgesic), Isoxsuprine HCl (tocolytic), Ondansetron (antiemetic) and amoxicillin (antibiotic). Based on drugs to the fetus, drugs prescribed to pregnant women are included in categories A, B, C and D. In conclusion, the most prescriptions for pregnant women are vitamin and mineral supplements, analgesics, and tocolytic drugs.
Bloor M, Paech M.J, Kaye R. Tramadol in pregnancy and lactation. International Journal of Obstetric Anesthesia Feb 2012. 21(2):163-7
Bremer, L. et al 2017. Paracetamol Medication During Pregnancy: Insights on Intake Frequencies, Dosages and Effects on Hematopoietic Stem Cell Populations in Cord Blood from a Longitudinal Prospective Pregnancy Cohort. EBioMedicine. 26, pp. 146–151
Briggs, G.G., Freeman, R.K., and Yaffe, S.J., 2002. Drugs in Pregnancy and Lactation. 6 th Ed. Philadelphia: Lippincott Williams & Wilkins, p.10.
Depkes RI. 2006. Pedoman Pelayanan Farms untuk Ibu Hamil dan Menyusui, Direktorat Bina Farmasi Komunitas dan Klinik Departemen Kesehatan RI, Jakarta.
DiPiro J, Talbert R, Yee G, Matzke G, Wells B, Posey L. Pharmacotherapy: A pathophysiologic approach, Edisi ke-7. New York: The McGraw-Hill Companies Inc; 2014
Masliyana. Gambaran Penggunaan Obat Pada Pasien Ibu Hamil Di Poliklinik Obstetri Dan Ginekologi Di Rsud Kotapinang Kabupaten Labuhanbatu Selatan. Jurnal Dunia Farms. No 2 (2019)
Medscape.com, diakses tanggal 10 Mei 2022
Siregar, S.S., 2016. Penggunaan Obat pada Ibu Hamil. Jakarta: Institut Sains dan Teknologi Nasional. Skripsi.
Slater.J, Quinten C, Candore, Pinheiro L. Ondansetron use in nausea and vomiting during pregnancy: A descriptive analysis of prescription patterns and patient characteristics in UK general practice.2022. https://doi.org/10.1111/bcp.15370
Sloane& Benedict. 2009. Petunjuk lengkap kehamilan. Alih Bahasa, Anton Adiwiyoto. Jakarta: Pustaka Mina. Lacy, C. F., L. L. Armstrong, M. P. Goldman, dan L. L. Lance. 2006. Drug Information Handbook, 14th Edition. Hudson: Lexi-Comp Inc.]
Slattery J. et al.Ondansetron use in nausea and vomiting during pregnancy: A descriptive analysis of prescription patterns and patient characteristics in UK general practice. Br J Clin Pharmacol. 2022 Apr 28. doi: 10.1111/bcp.15370.
Tramadol. 2020. M. Bloor et al.Tramadol in pregnancy and lactation Int. J. Obstet. Anesth. (2012)
Ummah et al. Profil Penggunaan Obat Pada Ibu Hamil Dan Menyusui Di Wilayah Surabaya. Jurnal Farmasi KomunitasVol. 5, No. 1, (2018) 10-17.
Copyright (c) 2022 Endang Susilowati
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.