Profile of Drug Adherence in Elderly Patients with Oral Antidiabetes And Antihipertensive Therapy Using Pill Count Method
Profil Kepatuhan Minum Obat Pasien Lansia Dengan Terapi Oral Antidiabetes Dan Antihipertensi Metode Pill Count
Keywords:
Oral antidiabetes, Oral Antihypertension, Elderly patients, Adherence
Abstract
Medication adherance is a problem by the elderly. This study was conducted to evaluate adherence to taking oral antidiabetic drugs and oral antihypertensive drugs in elderly patients using the pill count method at one of the health centers in South Surabaya. The pill count method in this study was chosen because it can provide an overview of the profile of medication adherence for elderly patients who receive oral antidiabetic and oral antihypertensive drugs by calculating the remaining medication based on the dosage and the rules for taking the drug when the patient returns to control. This study was observational with prospective observations and data were analyzed descriptively. The number of samples in this study were 30 elderly patients. The results obtained were that the most oral antidiabates drugs were given the Sulfonylurea combination Biguanida drug class, namely Glibenclamide 5 mg combination Metformin 500 mg (66.7%), while for oral antidiabates therapy the single administration was the calcium channel blocker is Amlodipine 5 mg (76 %). In the results of medication adherence, it was found that 63.3% of patients adherance to taking oral antidiabetic drugs and not adherance is 36,7%. While 70.0% of patients were adherence to taking oral antihypertension drugs and not adherance is 30%. Patients who consumed 2 drug combinations were 53.3% more adherent than those who consumed 3 to 5 drug combinations of 46.7%.References
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2. Osterberg Lars BT. Adherence to medication. N Engl J Med. 2005;55(2):487–97.
3. Wijaya IN, Faturrohmah A, Agustin WW, Soesanto TG, Kartika D, Prasasti H. Profil kepatuhan pasien diabetes melitus Puskesmas wilayah Surabaya Timur dalam menggunakan obat dengan metode pill count. J Farm Komunitas [Internet]. 2015;2(1):18–22. Available from: http://journal.unair.ac.id/download-fullpapers-jfkb5969c2ab7full.pdf
4. Sammulia SF. Perbandingan Pill Box Dan Medication Chart Dalam Meningkatkan Kepatuhan Dan Outcome Klinik Geriatri Kota Comparative Pill Box And Medication Chart On The Levels Compliance. J Manaj dan Pelayanan Farm. 2016;6(4):288–96.
5. Saibi Y, Romadhon R, Nasir NM. Kepatuhan Terhadap Pengobatan Pasien Diabetes Melitus Tipe 2 di Puskesmas Jakarta Timur. J Farm Galen (Galenika J Pharmacy). 2020;6(1):94–103.
6. Kautzky-Willer A, Harreiter J, Pacini G. Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus. Endocr Rev. 2016;37(3):278–316.
7. Kemenkes RI. Peraturan Menteri Kesehatn Republik Indonesia Nomor 67 Tahun 2015 Tentang Penyelenggaraan Pelayanan Kesehatan Lanjut Usia di Pusat Kesehatan Masyarakat . Jakarta. In 2015. p. 1–27.
8. WHO. World Report on Ageing and Health 2015. 2015.
9. Soelistijo S, Lindarto D, Decroli E, Permana H, Sucipto K, Kusnadi Y et al. Pengelolaan Dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia. Perkeni. 2019. 133 p.
10. González-Ortiz M, Guerrero-Romero JF, Violante-Ortiz R, Wacher-Rodarte N, Martínez-Abundis E, Aguilar-Salinas C, et al. Efficacy of glimepiride/metformin combination versus glibenclamide/metformin in patients with uncontrolled type 2 diabetes mellitus. J Diabetes Complications. 2009;23(6):376–9.
11. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA - J Am Med Assoc. 2014;311(5):507–20.
12. Fares H, DiNicolantonio JJ, O’Keefe JH, Lavie CJ. Amlodipine in hypertension: A first-line agent with efficacy for improving blood pressure and patient outcomes. Open Hear. 2016;3(2).
13. Park CG. Is amlodipine more cardioprotective than other antihypertensive drug classes? Korean J Intern Med. 2014;29(3):301–4.
14. Destro M, Cagnoni F, D’Ospina A, Ricci AR, Demichele E, Peros E, et al. Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: An update. Vasc Health Risk Manag. 2010;6(1):253–60.
15. Mokolomban C, Wiyono WI, Mpila DA. Kepatuhan Minum Obat Pada Pasien Diabetes Melitus Tipe 2 Disertai Hipertensi Dengan Menggunakan Metode Mmas-8. Pharmacon. 2018;7(4):69–78.
Published
2023-07-17
How to Cite
Mas Ulfa, N. (2023). Profile of Drug Adherence in Elderly Patients with Oral Antidiabetes And Antihipertensive Therapy Using Pill Count Method: Profil Kepatuhan Minum Obat Pasien Lansia Dengan Terapi Oral Antidiabetes Dan Antihipertensi Metode Pill Count. Journal Pharmasci (Journal of Pharmacy and Science), 8(2), 103-109. https://doi.org/10.53342/pharmasci.v8i2.352
Section
Articles
Copyright (c) 2023 Ninik Mas Ulfa
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