Formulation of Handwash Essential Oil and Hydrosol of Lime Peel (Citrus aurantifolia) as Antibacterials: Formulasi Handwash Minyak Atsiri dan Hidrosol Kulit Jeruk Nipis (Citrus aurantifolia) Sebagai Antibakteri

Wahidah Asni; Vita Olivia Siregar; Rolan Rusli

doi:10.53342/pharmasci.vi.409

Authors

Wahidah Asni Mahasiswa Program Studi Farmasi, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Vita Olivia Siregar Laboratorium Penelitian dan Pengembangan FARMAKA TROPIS, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Rolan Rusli Laboratorium Penelitian dan Pengembangan FARMAKA TROPIS, Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

DOI:

https://doi.org/10.53342/pharmasci.vi.409

Keywords:

Essential oil, Hydrosol, Handwash, Lime peel

Abstract

The hand is the body part that most frequently comes into contact with the external environment and is used in daily activities. This facilitates contact with microorganisms and the possibility of transferring to other objects. One of the natural ingredients that can be utilized as an antibacterial is lime (Citrus aurantifolia). The purpose of this study was to obtain a handwash preparation containing essential oil and lime peel hydrosol with antibacterial activity and characteristic results and physical stability in accordance with the requirements. This research method is laboratory experimental research with qualitative and quantitative methods. The results showed that the characteristics of the handwash preparation in the organoleptic test, pH, soap stability, and specific gravity met the requirements. Lime peel essential oil and hydrosol handwash preparations have antibacterial activity in the strong to very strong category with the diameter of the kill zone at concentrations of 10%, 17.5%, and 25% being 19.64 mm; 21.79 mm; 19.69 mm on Escherichia coli bacteria and 19.23 mm; 22.32 mm, and 20.66 mm on Staphylococcus aureus bacteria, respectively.

References

1] Pratami, H. A., Apriliana, E., & Rukmono, P. (2013). Identifikasi mikroorganisme pada tangan tenaga medis dan Paramedis di Unit Perinatologi Rumah Sakit Abdul Moeloek Bandar Lampung. Medical Journal Of Lampung University, 85â€“94.

[2] Hasibuan, R., Adventi, F., & Persaulian, R. (2019). Pengaruh Suhu Reaksi, Kecepatan Pengadukan dan Waktu Reaksi pada Pembuatan Sabun Padat dari Minyak Kelapa (Cocos nucifera L.). Jurnal Teknik Kimia USU, 8(1), 11â€“17.

[3] Santoso, A., Suryadarma, I. B., Sumari, S., & Sukarianingsih, D. (2020). Pembuatan Sabun Aroma Teraphi untuk Masyarakat Pedesaan. Jurnal KARINOV, 3(1), 5.

[4] Sreepian, A., Popruk, S., Nutalai, D., Phutthanu, C., & Sreepian, P. M. (2022). Antibacterial Activities and Synergistic Interaction of Citrus Essential Oils and Limonene with Gentamicin against Clinically Isolated Methicillin-Resistant Staphylococcus aureus.

[5] Wong, M. (2017). Uji Aktivitas Antibakteri Minyak Atsiri Kulit Buah Jeruk Nipis (Citrus aurantifolia Swingle) Terhadap Streptococcus pyogenes. Doctoral Dissertation, Widya Mand.

[6] Murti, I. K. A. Y., Putra, I. P. S. A., N.N.K.T., S., Wijayanti, N. P. D., & Yustiantara, P. S. (2018). Optimasi Konsentrasi Olive Oil Tehadap Stabilitas Fisik Sediaan Sabun Cair. Jurnal Farmasi Udayana, 6(2), 15.

[7] Hutauruk, H., Yamlean, P. V. Y., & Wiyono, W. (2020). Formulasi Dan Uji Aktivitas Sabun Cair Ekstrak Etanol Herba Seledri (Apium graveolens L) Terhadap Bakteri Staphylococcus aureus. Pharmacon, 9(1), 73.

[8] Rusli, N., Nurhikma, E., & Sari, E. P. (2019). Formulasi Sediaan Sabun Padat Ekstrak Daun Lamun (Thalassia hemprichii). Warta Farmasi, 8(2), 53â€“62.

[9] Dewi Wulandari, D. F. A. dan A. A. (2018). dan Akhyar Ali 1 1. 4(April), 1â€“9.

[10] Eloff, J. N. (2019). Avoiding pitfalls in determining antimicrobial activity of plant extracts and publishing the result. BMC Complementary and Alternative Medicine, 19(1), 106.