Analysis of Treatment Compliance Level and the Relationship With Quality Of Life, New York Heart Association (NYHA) Classification, and Rehospitalization In Chronic Heart Failure Patients

Authors

  • Wenny Putri Nilamsari Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga
  • Neni Tri Astuti Master of Clinical Pharmacy Program Department of Pharmacy Practice, Universitas Airlangga, Surabaya, Indonesia
  • Wanudya Atmajani Master of Clinical Pharmacy Program Department of Pharmacy Practice, Universitas Airlangga
  • Budi Suprapti Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga
  • Hendri Susilo Department of Cardiology, Teaching Hospital of Universitas Airlangga, Surabaya

DOI:

https://doi.org/10.53342/pharmasci.v11i1.565

Keywords:

Chronic Heart Failure,, Compliance,, Quality Of Life,, Nyha Classification,, Rehospitalization,

Abstract

Background: Patient non-compliance with heart failure treatment is associated with increased rehospitalization, deteriorating symptoms, decreased quality of life, and death. Therefore, this study aimed to examine compliance with chronic heart failure treatment and the relationship with quality of life, New York Heart Association (NYHA) classification, and rehospitalization.

Method: A cross-sectional study of chronic heart failure patients was carried out at Airlangga University Hospital (RSUA) from April to June 2023. The inclusion criteria include patients aged >18 years, signed informed consent, able to read, write, and had no difficulty communicating. Meanwhile, the exclusion criteria were chronic heart failure patients with no known history of rehospitalization.

Results: The results showed that 41% of heart failure patients were compliant with RAASi, beta-blockers, MRA, and furosemide. Compliance with RAASi had a positive relationship with NYHA classification. However, a negative relationship was found between overall medication compliance and rehospitalization. There was no relationship between RAASi, beta-blockers, MRA, and furosemide compliance with the incidence of rehospitalization.

Conclusion: A positive relationship was found between compliance and RAASi medication with NYHA classification, while medication compliance to the incidence of rehospitalization showed a negative relationship.

 

Keywords: Chronic Heart Failure, Compliance, Quality of Life, NYHA Classification, Rehospitalization

 

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Published

2026-01-15

How to Cite

Analysis of Treatment Compliance Level and the Relationship With Quality Of Life, New York Heart Association (NYHA) Classification, and Rehospitalization In Chronic Heart Failure Patients. (2026). Journal Pharmasci (Journal of Pharmacy and Science), 11(1), 68-80. https://doi.org/10.53342/pharmasci.v11i1.565